CHAPTER 41 HEALTH: EPIDEMIOLOGY
subchapter 41A communicable disease control
section .0100 reporting of communicable diseases
10A ncac 41a .0101 REPORTABLE DISEASES AND CONDITIONS
(a) The following named diseases and conditions are declared to be dangerous to the public health and are hereby made reportable within the time period specified after the disease or condition is reasonably suspected to exist:
(1) acquired immune deficiency syndrome (AIDS) ‑ 24 hours;
(2) anthrax ‑ immediately;
(3) botulism ‑ immediately;
(4) brucellosis ‑ 7 days;
(5) campylobacter infection ‑ 24 hours;
(6) chancroid ‑ 24 hours;
(7) chlamydial infection (laboratory confirmed) ‑ 7 days;
(8) cholera ‑ 24 hours;
(9) Creutzfeldt-Jakob disease 7 days;
(10) cryptosporidiosis - 24 hours;
(11) cyclosporiasis - 24 hours;
(12) dengue ‑ 7 days;
(13) diphtheria ‑ 24 hours;
(14) Escherichia coli, shiga toxin-producing ‑ 24 hours;
(15) ehrlichiosis - 7 days;
(16) encephalitis, arboviral ‑ 7 days;
(17) foodborne disease, including Clostridium perfringens, staphylococcal, Bacillus cereus, and other and unknown causes ‑ 24 hours;
(18) gonorrhea ‑ 24 hours;
(19) granuloma inguinale ‑ 24 hours;
(20) Haemophilus influenzae, invasive disease ‑ 24 hours;
(21) Hantavirus infection 7 days;
(22) Hemolytic-uremic syndrome 24 hours;
(23) Hemorrhagic fever virus infection immediately;
(24) hepatitis A ‑ 24 hours;
(25) hepatitis B ‑ 24 hours;
(26) hepatitis B carriage ‑ 7 days;
(27) hepatitis C, acute - 7 days;
(28) human immunodeficiency virus (HIV) infection confirmed ‑ 24 hours;
(29) influenza virus infection causing death - 24 hours;
(30) legionellosis ‑ 7 days;
(31) leprosy 7 days;
(32) leptospirosis ‑ 7 days;
(33) listeriosis 24 hours;
(34) Lyme disease ‑ 7 days;
(35) lymphogranuloma venereum ‑ 7 days;
(36) malaria ‑ 7 days;
(37) measles (rubeola) ‑ 24 hours;
(38) meningitis, pneumococcal ‑ 7 days;
(39) meningococcal disease ‑ 24 hours;
(40) monkeypox 24 hours;
(41) mumps ‑ 7 days;
(42) nongonococcal urethritis ‑ 7 days;
(43) novel influenza virus infection immediately;
(44) plague ‑ immediately;
(45) paralytic poliomyelitis ‑ 24 hours;
(46) pelvic inflammatory disease 7 days;
(47) psittacosis ‑ 7 days;
(48) Q fever ‑ 7 days;
(49) rabies, human ‑ 24 hours;
(50) Rocky Mountain spotted fever ‑ 7 days;
(51) rubella ‑ 24 hours;
(52) rubella congenital syndrome ‑ 7 days;
(53) salmonellosis ‑ 24 hours;
(54) severe acute respiratory syndrome (SARS) 24 hours;
(55) shigellosis ‑ 24 hours;
(56) smallpox immediately;
(57) Staphylococcus aureus with reduced susceptibility to vancomycin 24 hours;
(58) streptococcal infection, Group A, invasive disease - 7 days;
(59) syphilis ‑ 24 hours;
(60) tetanus ‑ 7 days;
(61) toxic shock syndrome ‑ 7 days;
(62) trichinosis ‑ 7 days;
(63) tuberculosis ‑ 24 hours;
(64) tularemia ‑ immediately;
(65) typhoid ‑ 24 hours;
(66) typhoid carriage (Salmonella typhi) ‑ 7 days;
(67) typhus, epidemic (louse-borne) ‑ 7 days;
(68) vaccinia 24 hours;
(69) vibrio infection (other than cholera) - 24 hours;
(70) whooping cough ‑ 24 hours;
(71) yellow fever ‑ 7 days.
(b) For purposes of reporting, confirmed human immunodeficiency virus (HIV) infection is defined as a positive virus culture, repeatedly reactive EIA antibody test confirmed by western blot or indirect immunofluorescent antibody test, positive nucleic acid detection (NAT) test, or other confirmed testing method approved by the Director of the State Public Health Laboratory conducted on or after February 1, 1990. In selecting additional tests for approval, the Director of the State Public Health Laboratory shall consider whether such tests have been approved by the federal Food and Drug Administration, recommended by the federal Centers for Disease Control and Prevention, and endorsed by the Association of Public Health Laboratories.
(c) In addition to the laboratory reports for Mycobacterium tuberculosis, Neisseria gonorrhoeae, and syphilis specified in G.S. 130A-139, laboratories shall report:
(1) Isolation or other specific identification of the following organisms or their products from human clinical specimens:
(A) Any hantavirus or hemorrhagic fever virus.
(B) Arthropod-borne virus (any type).
(C) Bacillus anthracis, the cause of anthrax.
(D) Bordetella pertussis, the cause of whooping cough (pertussis).
(E) Borrelia burgdorferi, the cause of Lyme disease (confirmed tests).
(F) Brucella spp., the causes of brucellosis.
(G) Campylobacter spp., the causes of campylobacteriosis.
(H) Chlamydia trachomatis, the cause of genital chlamydial infection, conjunctivitis (adult and newborn) and pneumonia of newborns.
(I) Clostridium botulinum, a cause of botulism.
(J) Clostridium tetani, the cause of tetanus.
(K) Corynebacterium diphtheriae, the cause of diphtheria.
(L) Coxiella burnetii, the cause of Q fever.
(M) Cryptosporidium parvum, the cause of human cryptosporidiosis.
(N) Cyclospora cayetanesis, the cause of cyclosporiasis.
(O) Ehrlichia spp., the causes of ehrlichiosis.
(P) Shiga toxin-producing Escherichia coli, a cause of hemorrhagic colitis, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura.
(Q) Francisella tularensis, the cause of tularemia.
(R) Hepatitis B virus or any component thereof, such as hepatitis B surface antigen.
(S) Human Immunodeficiency Virus, the cause of AIDS.
(T) Legionella spp., the causes of legionellosis.
(U) Leptospira spp., the causes of leptospirosis.
(V) Listeria monocytogenes, the cause of listeriosis.
(X) Mycobacterium leprae, the cause of leprosy.
(Y) Plasmodium falciparum, P. malariae, P. ovale, and P. vivax, the causes of malaria in humans.
(Z) Poliovirus (any), the cause of poliomyelitis.
(AA) Rabies virus.
(BB) Rickettsia rickettsii, the cause of Rocky Mountain spotted fever.
(CC) Rubella virus.
(DD) Salmonella spp., the causes of salmonellosis.
(EE) Shigella spp., the causes of shigellosis.
(FF) Smallpox virus, the cause of smallpox.
(GG) Staphylococcus aureus with reduced susceptibility to vanomycin.
(HH) Trichinella spiralis, the cause of trichinosis.
(II) Vaccinia virus.
(JJ) Vibrio spp., the causes of cholera and other vibrioses.
(KK) Yellow fever virus.
(LL) Yersinia pestis, the cause of plague.
(2) Isolation or other specific identification of the following organisms from normally sterile human body sites:
(A) Group A Streptococcus pyogenes (group A streptococci).
(B) Haemophilus influenzae, serotype b.
(C) Neisseria meningitidis, the cause of meningococcal disease.
(3) Positive serologic test results, as specified, for the following infections:
(A) Fourfold or greater changes or equivalent changes in serum antibody titers to:
(i) Any arthropod-borne viruses associated with meningitis or encephalitis in a human.
(ii) Any hantavirus or hemorrhagic fever virus.
(iii) Chlamydia psittaci, the cause of psittacosis.
(iv) Coxiella burnetii, the cause of Q fever.
(v) Dengue virus.
(vi) Ehrlichia spp., the causes of ehrlichiosis.
(vii) Measles (rubeola) virus.
(viii) Mumps virus.
(ix) Rickettsia rickettsii, the cause of Rocky Mountain spotted fever.
(x) Rubella virus.
(xi) Yellow fever virus.
(B) The presence of IgM serum antibodies to:
(i) Chlamydia psittaci
(ii) Hepatitis A virus.
(iii) Hepatitis B virus core antigen.
(iv) Rubella virus.
(v) Rubeola (measles) virus.
(vi) Yellow fever virus.
(4) Laboratory results from tests to determine the absolute and relative counts for the T-helper (CD4) subset of lymphocytes that have a level below that specified by the Centers for Disease Control and Prevention as the criteria used to define an AIDS diagnosis.
History Note: Authority G.S. 130A-134; 130A-135; 130A-139; 130A-141;
Temporary Rule Eff. February 1, 1988, for a period of 180 days to expire on July 29, 1988;
Eff. March 1, 1988;
Amended Eff. October 1, 1994; February 1, 1990;
Temporary Amendment Eff. July 1, 1997;
Amended Eff. August 1, 1998;
Temporary Amendment Eff. February 13, 2003; October 1, 2002; February 18, 2002; June 1, 2001;
Amended Eff. April 1, 2003;
Temporary Amendment Eff. November 1, 2003; May 16, 2003;
Amended Eff. January 1, 2005; April 1, 2004;
Temporary Amendment Eff. June 1, 2006;
Amended Eff. April 1, 2008; November 1, 2007; October 1, 2006;
Temporary Amendment Eff. January 1, 2010;
Temporary Amendment Expired September 11, 2010;
Amended Eff. April 1, 2011.